The Health Sciences Library supports teaching, research and patient care in six programs: Dental Medicine, Health Technology and Management, Medicine, Nursing, Public Health, and Social Welfare. The Library also supports research and patient care for the University Hospital and the Long Island State Veterans Home.

It is an area library for the National Network of Libraries of Medicine administered by the National Library of Medicine, a member of NERL, the consortia of distinguished research universities, ARL (Association of Research Libraries), and RLG (Research Libraries Group). It also functions as a regional resource assisting health care professionals throughout Nassau and Suffolk counties.

The library maintains a current print collection of over 280,000 serial and monograph volumes, more than 75,000 books, more than 750 electronic books, over 500 print professional healthcare and biomedical journals, and nearly 3,200 electronic journals. Additionally, the library supports access to over 110 primarily web-based electronic research databases, including ACCESSMedicine, MDConsult, Ovid MEDLINE, ScienceDirect, UpToDate and Web of Science. The Library offers numerous classes on improving the effectiveness of managing information resources.